First baby born following uterus transplant from deceased donor: case study

A medical team in São Paulo with a baby born via a uterine transplant.									Divulgação

The transplanted uterus was removed during the caesarean section and showed no anomalies.

Uterus transplants have become more common in recent years, resulting in 11 live births around the world. "This would increase the availability of the uterus as living donors are always in scarcity", Ranjana Sharma, Senior Consultant, (Obstetrics and Gynaecology), Indraprastha Apollo Hospitals, New Delhi, told IANS.

The baby girl was born in Sao Paulo, Brazil, late past year following a successful 10 hour uterus transplant to a patient who had been born without a womb. Uterine transplantation began in other countries where there are legal or ethical barriers to surrogacy-getting someone else to carry the pregnancy-O'Neill says.

"The Brazilian group has proven that using deceased donors is a viable option", said the clinic's Dr. Tommaso Falcone, who was involved in the OH case. In the first, the uterus had to be removed from the recipient after an infection occurred; Flyckt said she couldn't say where things stood with the second case other than that the recipient was doing well.

Being able to use the uterus from deceased patients opens up the possibility of more organs being available but in the ten attempts so far only this most recent birth has resulted in a successful birth.

The first living donor womb transplant was performed in Sweden in 2013.

In the USA, around 10 percent of women aged between 15 to 44 struggle with fertility, according to the Centers for Disease Control and Prevention.

"The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility", says Dr. Dani Ejzenberg.

"The number of people willing and committed to donate organs upon their own death are far larger than those of live donors, offering a much wider potential donor population".

The surgery took place in September 2016.

Tyler Perry pays off more than $430,000 in layaways ahead of Christmas
Tyler Perry is in the spirit of the season. "I was trying to do this anonymously", Perry said in a Twitter video posted on Thursday.

The baby girl's mother was born without a uterus as a result of Mayer-Rokitansky-Kuster-Hauser syndrome a rare disorder that affects a woman's reproductive system. Seven months after the transplant, doctors transferred an embryo made via in-vitro fertilization from the woman's egg and her husband's sperm into her womb.

The uterus was donated by a 45-year-old deceased mother of three, who died from a subarachnoid hemorrhage.

In this case the 61 year old donor was alive and well at the time, generously giving up her uterus for the cutting-edge operation.

The procedure involved connecting the donor uterus to the veins, arteries, ligaments and vaginal canals of the 32-year-old.

After surgery, the anonymous recipient remained in intensive care for two days before spending another six days on a specialised transplant ward.

To prevent her body from rejecting the new organ, the woman was given five different drugs, along with antimicrobials, anti-blood clotting treatments, and aspirin.

After five months, the uterus showed no sign of rejection, ultrasound scans were normal, and the woman was menstruating regularly.

In this trial, the mother was given standard doses of immune suppression medications for nearly six months, with positive results, before implantation of the embryo was completed.

It also "eliminates the main challenge", Singer added, "which is finding a matching donor and risking the lives of live donors who have to otherwise undergo a major surgery to remove their uterus".

Related News:

  • Contemporary Study Portrays Just How Frantically Speedily Greenland Is Melting

    Contemporary Study Portrays Just How Frantically Speedily Greenland Is Melting

    Another noteworthy aspect of the findings is how little additional warming it now takes to cause huge spikes in ice sheet melting. This is the melting of the Greenland shield is one of the most important factors influencing the increase in global sea level.
    USA  military carries out Open Skies flight over Ukraine

    USA military carries out Open Skies flight over Ukraine

    The observation flight was requested under the Open Skies Treaty by the Arms Control Directorate of the Ukrainian General Staff. The Open Skies Treaty allows signatory states to gather information about the military activities of other member countries.
    Mortal Kombat 11 Revealed, Looks Characteristically Gory, OTT

    Mortal Kombat 11 Revealed, Looks Characteristically Gory, OTT

    The next Mortal Kombat will be out sooner than many expected, with a full reveal event planned for next month. The song playing during the Mortal Kombat 11 trailer is called Immortal by 21 Savage.
  • US Warship Poses Free Navigation 'Challenge' to Russian Federation

    US Warship Poses Free Navigation 'Challenge' to Russian Federation

    A spokesman for Putin said in response that a hoped-for U.S. -Russia summit in Washington " is now out of the question ". Pacific Fleet acknowledged the move by the USS McCampbell was a "challenge" to Russia, CNN reported .
    VW's final generation of petrol engines will come in 2026

    VW's final generation of petrol engines will come in 2026

    As Volkswagen's chief strategist, Michael Jost, explained "We're gradually fading out combustion engines to the absolute minimum". By 2030, VW says it will offer hybrid or electric versions of its entire 300-plus-vehicle lineup.
    Cheesecake Factory giveaway draws crowds, leading to clogged roads and fistfights

    Cheesecake Factory giveaway draws crowds, leading to clogged roads and fistfights

    A DoorDash spokesperson told Fox News they are 'aware of this incident, and are cooperating with local law enforcement'. Savage says the individual requested medical attention after the altercation and was taken to a hospital.
  • China promises prompt action on US trade pact

    China promises prompt action on US trade pact

    China has said it will import more USA products to reduce its trade surplus, but no dollar amount has been publicly discussed.
    Fred Hoiberg fired as Chicago Bulls coach

    Fred Hoiberg fired as Chicago Bulls coach

    Additionally, he has coached collegiately at Michigan State, where he served on the staffs for both Jud Heathcote and Tom Izzo. After an ugly 5-19 start to the season, the Bulls chose to fire Hoiberg, who was in the fourth season of a five-year contract.
    WashPost: Ocasio-Cortez Claim About Pentagon Wrong

    WashPost: Ocasio-Cortez Claim About Pentagon Wrong

    She cited the $21 trillion figure and said '66 percent of Medicare for All could have been funded already by the Pentagon'. She also gave insight into congressional budgeting saying that each member gets a $20,000 budget for interns.
  • Who is Annegret Kramp-Karrenbauer, the new leader of Germany's CDU?

    Who is Annegret Kramp-Karrenbauer, the new leader of Germany's CDU?

    They were said to be reasonably close, and the lack of communication between the two raised eyebrows at the time. She reported members were full of "pride, frustration, concern and uncertainty".
    CNN’s NY  offices evacuated due to bomb threat

    CNN’s NY offices evacuated due to bomb threat

    That package was addressed to former CIA Director John Brennan, who was a contributor to the network for a time. Lemon said fire alarms rang and a loudspeaker told them they needed to evacuate during his live show.
    Persona 5's Joker Will Be Super Smash Bros Ultimate DLC

    Persona 5's Joker Will Be Super Smash Bros Ultimate DLC

    When Reggie Fils-Aime, President of Nintendo of America, appeared after the reveal, he noted that all of the Super Smash Bros . Sadly, Nintendo didn't have anything else to reveal about the new character - no in game footage, no screenshots and no hints.


Most liked

B.C. Government releases climate change plan
A previous version said net-zero energy buildings would generate enough on-site energy to power their own functions. The Sierra Club BC's campaigns director Caitlyn Vernon said the plan has transparent reporting and accountability.

‘Dauntless’ Confirmed For Consoles, Coming In 2019
Following the announcement and trailer for Dauntless at The Game Awards 2018, some fresh details have landed. Dauntless is now in open beta on PC and Phoenix Labs has confirmed that the game will continually evolve.

Rap star Kendrick Lamar leads Grammy nominations with 8
On the flip side of that equation is best new artist nominee Margo Price, who has been releasing independent music since 2010. He didn't run away with the crown, though, as Drake was right behind him with seven nominations of his own.

Deontay Wilder makes it clear he wants rematch against Tyson Fury
And Finkel, Wilder's co-manager, established that the American's camp would require talks to be more discreet this time. The bout ended in a controversial draw when the judges delivered harsh verdicts against the Gypsy King.

‘Stranger Things 3: The Game’ Announced, First Trailer Revealed
The awkwardly-titled Stranger Things 3: The Game is a 16-bit adaption that follows the events of Season 3. Like the series itself! However, we can expect both to arrive around the same time, sometime in 2019.

Kyler Murray, the quintessential Oklahoma Sooners quarterback
This marks the third year in a row the Sooners have had a Heisman finalist , becoming the sixth school to accomplish that feat. He is a finalist for the award with Ohio State quarterback Dwayne Haskins and Alabama quarterback Tua Tagovailoa .

China-US Ceasefire Paves Way For New LNG Projects
He added that Xi has sought to control the Indo-Pacific region, where the USA previously had significance. One Chinese official said officials were "waiting for the leaders to return" before publicising details.

Imran Khan: Pakistan will no longer be America's hired gun
Khan also termed the USA policy of declaring people criticizing American policies as "imperialistic approach". Defending ties with Beijing, the PM said our relationship with China is not one-dimensional.

North Carolina GOP leader says he's "horrified" by allegations of election fraud
That's a shift for Woodhouse, who previously dismissed such calls as a Democratic attempt to steal the election from Harris. The unofficial tally of results had Harris winning the race in southeastern North Carolina by a little over 900 votes.

US Braces To Sail Warship Into Black Sea Amidst Russia Ukraine Conflict
NATO , which includes several Black Sea member states, and the United States have routinely sent warships patrolling the Black Sea , despite Russian concerns.

Why have seals been getting eels stuck up their noses?
A juvenile Hawaiian Monk Seal found itself in a spot of bother earlier this week when a sizeable eel became lodged in its nose. Regardless, we're happy to hear this sweet, vaguely irritated monk seal has been returned to its normal, eel-less state.

Death-row inmate awaiting word from court on stay of execution
Mr Dunham said he was not aware of any state other than Tennessee where inmates were choosing electrocution over lethal injection. Their case was thrown out, largely because a judge said they failed to prove a more humane alternative was available.

China trade truce gives global stocks and oil a big lift
And Stephen Innes, head of Asia-Pacific trade at OANDA said there was "complete confusion" over details of the Trump-Xi deal. MSCI's all-country world index climbed 0.8 per cent in its sixth straight day of gains and hit its highest since November 9.

Ecuador's president says Julian Assange should leave embassy soon
Assange fears he could face the death penalty for his role in the USA for leaking classified information. The investigation was later dropped, but Great Britain says he will be arrested if leaves the embassy .

Liverpool's Klopp criticises Burnley approach after Gomez injury
"Joe's injured and probably not only a little bit", said Klopp after the 3-1 win at Turf Moor. Following the match, Klopp gave an update on the Gomez injury, saying : "It was his ankle".