Processed Meats, Mania Disorder Risk Linked in New Research

Tom Jones

"It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated maniac episodes", explained Seva Khambadkone, doctoral student at the varsity.

Scientists are of the opinion that this could be due to the presence of chemical nitrate present in the foods to preserve them. He and colleagues collected demographic, health, and dietary data on 1,101 individuals with and without psychiatric disorders.

Nitrates have always been used as preservatives in cured meat products and have been previously linked to some cancers and neurodegenerative diseases.

Experiments in rats by the researchers showed that mania-like hyperactivity after just a few weeks on diets with added nitrates.

Trump Doesn’t Get Why U.S. Has to Defend NATO Allies
In 2014, every member of the alliance agreed that by 2024 they would each spend 2 percent of their national wealth on defense . The clause, known as Article 5 , has only ever been invoked one time, by the U.S. after the September 11, 2001 attacks.

The study can't prove that nitrates in foods actually cause mania, as only an association was seen.

Yolken says future studies could take a more in-depth look at the frequency and volume of nitrate consumption to help researchers understand more about any possible connection between nitrates and mania. "We looked at a number of different dietary exposures and cured meat really stood out", says Dr. Yolken. Yet when they analyzed the decades-worth of answers for any notable trends, the authors unexpectedly revealed that people who had been hospitalized for an episode of mania were 3.5 times more likely to have a history of eating nitrated cured meat compared with healthy control subjects (n=343) who filled out the same questionnaire, after adjusting for other potentially impacting factors. Within two weeks, the rats eating jerky showed irregular sleeping patterns and hyperactivity. They repeated the experiment, this time giving some rats the store-bought, nitrate-prepared jerky and others the nitrate-free formulation.

The study was published July 18 in the journal Molecular Psychiatry. "We tried to make sure the amount of nitrate used in the experiment was in the range of what people might reasonably be eating", Dr. Yolken comments". The theory, according to Johns Hopkins researchers, is that gut bacteria may be one contributing cause to mania and other brain disorders - which would mean that people with mania could reduce the frequency of their episodes by changing their diet. These animals also demonstrated changes to hippocampal pathways in the brain that have been implicated in human bipolar disorder, as well as alterations to their intestinal microbiota.

"Our results suggest that nitrated cured meat could be one environmental player in mediating mania", she said. It was partly funded by the U.S. National Institute of Mental Health. Between 2007 and 2017, researchers at the nearby Sheppard Pratt Health System asked 758 willing psychiatric patients to fill out comprehensive lifestyle questionnaires as part of a separate project.

Related News:



Most liked

UNC Football excited about addition of Javonte Williams
Suspensions pend on the results of the NCAA investigation, those Tar Heel players involved could be suspended for a game or more. And if it gets any safer, apparently, our national security is at stake.

My children dont see me as famous, says Britney Spears
This guy is really cute.' So then I called him, and ever since then. It takes your mind off of everything else'. I think that's really sexy for women".

MLB Rumors: Indians To Acquire All-Star Closer Brad Hand From Padres
A 9.5 K/9 while only allowing two home runs and one barreled hit in 48.1 innings is quite the impressive resume for Cimber. The Indians lost relievers Joe Smith and Brian Shaw to free agency, but the holdovers have struggled as well.

J.J. Abrams' Overlord Gets a New Release Date
Smith ( The Revenant ), the cast includes Jovan Adepo , Wyatt Russell , Pilou Asbæk , John Magaro , and Mathilde Ollivier . However, Paramount Pictures sold The Cloverfield Paradox to Netflix.

New Doctor Who Photos Bring the Gang Together
Whittaker will be joined by an all-new cast of characters in the series, including Bradley Walsh, Tosin Cole and Mandip Gill. The actor said she had been pleased with the reaction after it was announced she would be replacing Peter Capaldi .

Trump slams European Union over $5 billion fine on Google
They have denied European consumers the benefits of effective competition in the important mobile sphere. Despite the ongoing tensions, Mr Juncker insisted he was "upbeat and relaxed" ahead of his U.S. trip.

Smart, Celtics closing in on contract
After the Celtics lost in Game 7 of the Eastern Conference finals, Smart said that he's worth "more than 12-14 million". In 15 postseason games, he averaged 9.8 points, 5.3 assists and 3.7 rebounds in almost 30 minutes per game.

Manny Pacquiao Calls Out Floyd Mayweather For Rematch
Lucas Matthysse had already lost the fight even before he stepped into the ring against Manny Pacquiao Sunday noon in Kuala Lumpur.

Major League Baseball rumors: Manny Machado to Dodgers hits snag
A Platinum Glove Award victor and three-time All-Star at third base, Machado moved back to his original position this season.

It's a 'disgrace' Turkey won't release jailed pastor
Brunson and American officials have rejected all the claims. "I forgive those who lie and bear false witness against me". The continued imprisonment, and Turkey's purchase of a Russian air defense system, prompted the Republican-led U.S.

Princess Eugenie invites 1200 members of the public to her Windsor wedding
Like Meghan and Harry, the newlyweds will then undertake a short carriage procession through part of Windsor High Street. Thousands of royal fans also lined the streets of Windsor to see the couple. [It was a] complete surprise.

Sleepers to Watch at the 2018 Open Championship
Tiger Woods , however, said that controlling a driver that can potentially roll for 80 yards or more can make that strategy risky. Pretty amusing that the booth said there was "zero chance of getting this near within a couple of feet of the flagstick".

Newcastle boss Benitez admits he had Spain offer
Rafael Benitez admits he will have to "wheel and deal" this summer if he is to get the men he wants to rebuild Newcastle. Benitez's future is now in doubt as he waits for a significant breakthrough on the transfer front at St James' Park.

Watch Blue Origin launch its New Shepard spacecraft live right here
Meanwhile, Blue Origin's crew capsule coasted into space and safely re-entered the atmosphere before deploying parachutes to land. There is speculation that Bezos himself, the world's richest person, will be among the first people to fly on New Shepard.

Russian warship 'carrying £100 billion in gold' discovered off South Korea
Since its sinking, there have been numerous attempts to explore the remains of the ship and hunt for its purported treasure. They also identified the ship by comparing the various parts of it they found to historical blueprints.