Prostate cancer drug extends the lifespan of cancer patients

African-American men with prostate cancer show stronger response to hormone therapy | News-Medical

Professor de Bono said: "In the last few years immunotherapy has changed the way we treat many advanced cancers - but up to now no one had demonstrated a benefit in men with prostate cancer".

The team at the Institute of Cancer Research and the Royal Marsden Hospital in London said the results were "spectacular" and a "big deal".

FRIDAY, June 1, 2018 (HealthDay News) - Black men with advanced prostate cancer who get chemotherapy may live longer than white men, a new study suggests.

Professor Johann de Bono says, "I have these men who are dying, with weeks to months to live, whom we gave this drug to and had complete responses".

As such, they intend to explore this finding in a further trial to determine whether there is a particular subset of prostate cancer patients that might benefit most from immunotherapy.

The earlier trails conducted using immunotherapy in prostate cancer did not prove to be successful.

"This is the first prospective multicenter study by race of an anti-androgen hormonal therapy in advanced prostate cancer", George said.

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De Bono said that while patients with DNA fix mutations responded to treatment, further investigation is still needed to confirm this.

Nonetheless, for sufferers reminiscent of these within the new examine with docetaxel-refractory metastatic castration-resistant prostate most cancers, there may be at present no efficient therapy. While just 5 percent men who were a part of the trail actually saw their cancer to shrink or disappear after receiving the treatment, many of those had heavily mutated cancers.

Immunotherapy has become a treatment for cancer, particularly skin and lung cancers. The observations of the survey infer that more than third enrolled patients were alive and about one in ten patients, there was no significant growth in their cancer cells.

Unfortunately, only 10 - 15% of the patients responded to immunotherapy, making the approach ineffective for the majority of prostate cancer patients.

If patients who can respond to immunotherapy are identified, some of them may be able to avoid treatments that come with unwanted side effects.

"This new trial has found that testing for mutations in DNA fix genes could be a valuable marker of who will respond".

Aspherical 47,000 males are identified with prostate most cancers annually within the United Kingdom, with 11,631 deaths from the illness. In addition, they are more likely to be diagnosed at a younger age and with advanced, aggressive cancer, the researchers said.

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